Jan Chambers is resident designer for PlayMakers Repertory Company and design faculty in the Department of Dramatic Art at the University of North Carolina.

For PlayMakers Repertory Company she has designed: Sweeney Todd (set), 4000 Miles (set and costumes), Vanya, Sonia, Masha and Spike (costumes), Metamorphoses and the Tempest (in rep/ co-designed set and costumes), A Raisin in the Sun (costumes), The Making of a King: Henry IV – Parts One and Two and Henry V (in rep/ set), Fences (set), A Number (set and costumes), Angels in America Parts I and II (in rep/ costumes), The Life and Adventures of Nicholas Nickleby (costumes), TopDog/ UnderDog and Doubt (in rep/ costumes), Pericles (set), The Glass Menagerie (costumes/ co-design set), Crimes of the Heart (set and costumes), When the Bulbul Stopped Singing (set and costumes).

Other regional designs include: Guthrie Theatre: Pericles (set), Oregon Shakespeare Festival: Pericles (set) Henry V (costumes) The Folger Shakespeare Theatre: Pericles (set),  Hamlet (costumes), Charlotte Repertory Theatre: Signature (set and costumes), Carolina Ballet: Carmen (set), North Carolina Shakespeare Festival: Macbeth, The Miser (costumes), Profile Theater Project: Silver River (set and costumes), Victory Garden Theater: Hard Love (set), Merrimack Repertory: Lovers (set).

Jan is also the resident set and costume designer for Archipelago Theatre/CINE. Among her creations for Archipelago are the award winning environments for the originally scripted, devised works Out of the Blue, Woman in the Attic, Blue Roses, Eulogy for a Warrior, Ten in One and Those Women, as well as the recent acclaimed short film It Had Wings.